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Red cell antigens
Blood Groupings
The surface of the red cell consists of a bilipid membrane in which large protein molecules are embedded.
Major Genetic concepts of ABO system
Blood Groupings
In the ABO system there are three major groups and they are A, B and O
The ABO System
Blood Groupings
ABO grouping system is the most important test in medical laboratory and blood banking system Additional Test required under special conditions
Blood Groupings
More extensive testing is required whenever there is a disagreement
Rhesus Blood Group System
Blood Groupings
Levine and Stetson in 1939 reported an irregular antibody in a mother
Poly Agglutination
Blood Groupings
Most adult sera contain antibodies to these normally hidden antigens
Prozone Phenomenon and Titre
Blood Groupings
When a mixture of complete and incomplete antibodies are present in serum,
Antiglobulin Test (Coomb’s)
Blood Groupings
Coomb's Mourant and Race described a test for detecting non agglutinating Rh antibodies in serum
The Cross-match
Blood Groupings
The compatibility test between the donor and recepient is an important test performed in the blood bank
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